Cipheron on 18/9/2023 at 11:17
Quote Posted by Azaran
A new study adds additional credibility to zinc as a Covid treatment
There are articles stating that people with a zinc deficiency have worse Covid outcomes.
This would neatly explain why some studies say zinc does nothing while others find it had a good effect. It depends on where you do the study if you're not actually controlling for zinc deficiency levels.
How i read the overall results is that people who NEED the zinc can benefit from it, but there's no actual evidence that just giving zinc to everyone will help.
(
https://www.sciencedirect.com/science/article/pii/S120197122030730X)
Quote:
Patients with coronavirus disease 2019 (COVID-19) had significantly low zinc levels in comparison to healthy controls.
Zinc deficient patients developed more complications (70.4% vs 30.0%, p = 0.009).
Zinc deficient COVID-19 patients had a prolonged hospital stay (7.9 vs 5.7 days, p = 0.048).
In vitro studies have shown that reduced zinc levels favour the interaction of angiotensin-converting enzyme 2 (ACE2) with severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) spike protein and likewise that increased zinc levels inhibit ACE2 expression resulting in reduced viral interaction.
Azaran on 17/11/2023 at 15:09
After nearly 4 years, 7 Covid shots total, I finally got infected. Pretty sure I got it at an event last weekend.
First day was Tuesday, I had dry cough but nothing else; I thought it was due to dust in my apartment.
Wednesday felt a bit woozy, but tested negative. Again, thought my body was reacting to the dust somehow.
Yesterday woke up nauseous, coughing, almost vomited. Had mild fever, a bit tired and the same dry cough, tested positive, but totally fine otherwise, never bedridden or anything.
Today I'm totally fine save for the annoying cough.
The pre-Covid colds I remember having would leave me bedridden and delirious for about a week.
This is the LEAST sick I've ever been in my life.
Some friends gave me weird looks when said I had 7 Covid shots, but I'm now vindicated (everyone I know who had fewer shots had a harder time with it). I'm pretty sure all those shots are the reason it was so mild (I also took a ton of echinacea, and drank a lot of water, but the vaccines did the heavy lifting I'm sure).
lowenz on 17/11/2023 at 17:52
I'll get my annual shot the next week (to cover the last autumn and the winter season)
mxleader on 17/11/2023 at 18:36
I only have two Pfizer shots and then I got Covid. I have no idea if they helped reduce symptoms or if the Paxlovid treatment helped at all. I know it was a really shitty experience that I don't want to repeat. My brother has had several vaccinations and gets Covid like the common cold because he deals with a lot of the public that seem to travel a lot. I'm not ever sure if the tests are showing positive for Covid or just something similar because field tests are not always reliable. Of course in some areas of the world where seasonal colds and the flu hit people it's not easy to tell if you have one or more thing at once. Maybe I need to get a booster or just drink some beer.
nickie on 18/11/2023 at 16:43
As part of the UK Covid-19 Inquiry, members of the public are invited to share their experiences. Apparently there are a number of locations around the UK where live participation will be happening but so far I've only found Execter and Wrexham (over) and Carlisle. I can't find a central location list.
But if you can't/don't want to go in person you could take part in the (
https://covid19.public-inquiry.uk/every-story-matters/) Every Story Matters project.
I watched a couple of the early hearings, mostly starring Dominic Cummings (a creature, but interesting) and as far as I can tell, it was a complete clusterfuck of incompetence at No. 10. No surprise there then.
lowenz on 25/11/2023 at 22:07
Quote Posted by lowenz
I'll get my annual shot the next week (to cover the last autumn and the winter season)
Done, I'm still human and not a supermutant even after 5 shots :(
Situation here in Italy: (
https://lab24.ilsole24ore.com/coronavirus/?refresh_ce=1) (just translate in english)
Harvester on 5/1/2024 at 13:53
Latest post Covid syndrome news. Translated from Dutch by Google Translate.
Quote:
Dutch scientists unravel the major fatigue riddle of post-covid patients
Many post-covid patients become sicker and more tired after the slightest exertion. Amsterdam scientists have discovered that this has a physical cause. The power plants in patients' muscle cells function poorly and their muscle tissue dies.
Ellen de Visser / vk
'They were often no longer able to stand on their feet and were no longer approachable. Then they had to recover for days or weeks.”
The research results were published on Thursday in the journal Nature Communications. Of all post-covid patients, 70 percent suffer from so-called post-exertional malaise (PEM). This means that they collapse after sometimes the slightest physical or mental effort, after which their complaints worsen. The phenomenon contradicts the adage in medicine that exercise is healthy. Intensive rehabilitation often has a counterproductive effect on them. Patients are often told that the explanation is psychological.
A year later: how are these long Covid patients doing? “I wouldn't wish what I have on anyone”
These energy crashes largely explain why so many post-covid patients can no longer participate in society. Thousands of them have already been rejected.
To find out the cause of this mysterious phenomenon, infectious disease specialist Michèle van Vugt, professor at Amsterdam UMC, together with the VU's kinesiology department, set up a study among post-covid patients.
The researchers had 25 post-covid patients cycle as hard as possible for fifteen minutes and removed a piece of muscle tissue from their upper leg before and after the cycling test. They did the same with 21 people who had recovered after a corona infection.
'completely under'
Medical researcher Brent Appelman and sports scientist Rob Wüst saw it happen before their eyes. The post-covid patients barely made any progress and were 'completely destroyed' by the test, according to Appelman. 'They were often no longer able to stand on their feet and were no longer approachable. Then they had to recover for days or weeks.' Their hearts and lungs appeared to be fine, and they were not bedridden, so that could not explain their poor condition and their relapse.
Comparison of the biopsies from the two groups made it clear that there is a biological cause for this extreme fatigue. In post-covid patients, the damage to the muscle tissue after exercise is greater than in healthy people. Their mitochondria, the power plants in the cells, also function much less well.
Also read
The government does not have to give every long Covid patient an extra benefit
That explains why their physical and cognitive complaints worsen after exercise, says Appelman. Mitochondria are in all cells, including the brain, he explains. 'If we see energy problems in the muscles, they can also occur elsewhere.' Muscle damage also produces breakdown products that do the body no good.
'groundbreaking and very relevant'
Rotterdam pulmonologist Merel Hellemons calls the results 'groundbreaking and very relevant'. The research shows that the malaise patients experience after exertion can be explained, she says. 'We are gaining a better understanding of how this disease arises and hopefully also how we can treat it.'
Hellemons, not involved in the study, has seen many patients with post-covid at Erasmus MC in recent years and knows that they are faced with misunderstanding and lack of recognition. 'In regular research, abnormalities are almost never found in patients, but this study shows once again that these abnormalities are indeed present if we look more closely.'
It is still unclear why post-covid patients produce less energy in their cells. The Amsterdam scientists found higher concentrations of protein clumps between their muscle cells than in healthy people. It may be that they do not cause the energy problem but are actually the result of it.
Enzymes
Many scientists assume that remnants of the virus remain in the bodies of post-Covid patients that keep the immune system going. That would explain their complaints. The scientists at Amsterdam UMC found no indications of this in the muscles.
Appelman thinks that a possible cause can be found in an enzyme that continues to rage in the cells of post-covid patients. Last summer he and his Amsterdam colleagues published a study that provides indications for this. “We want to investigate that further.”
(
https://dx.doi.org/10.1038/s41467-023-44432-3) https://dx.doi.org/10.1038/s41467-023-44432-3
(
https://www.volkskrant.nl/wetenschap/een-leven-zonder-postcovid-ietsje-dichterbij-amsterdamse-wetenschappers-zitten-op-een-spoor~ba477769/) https://www.volkskrant.nl/wetenschap/een-leven-zonder-postcovid-ietsje-dichterbij-amsterdamse-wetenschappers-zitten-op-een-spoor~ba477769/
DuatDweller on 22/1/2024 at 18:27
Its funny I was supposed to the be paranoid of the area, but I didn't was no vax before, some friends insisted the vaccines were bad, and as a matter of fact, a woman vaccinated and got eyes problems (and still last), another man vaccinated in complete doses, and died anyway, a young man who was happening to be healthy got heart problems to the point he had to quit his job, some other woman got vaccinated and started feeling run down (not well at all). So I converted to my surprise to no vax. All people mentioned are well known and are real, they're not stories made up by some mad guy or something.
Sulphur on 23/1/2024 at 03:04
What's funny is anecdotal evidence being used to justify biases in decision-making. There's also the interesting thing that correlation != causation, but people don't usually examine that too hard because it's difficult to examine all the variables, and much easier to reduce it down to 'this thing must be responsible for all these disparate ills' without looking at it hard enough.
For the record, I managed to get shafted in a variety of ways, one of them including eye problems, from what I thought was covid - I did not have the vaccine at the time. What it turned out to be was undiagnosed hypertension exacerbated by covid.
DuatDweller on 23/1/2024 at 17:14
Quote Posted by Sulphur
What's funny is anecdotal evidence being used to justify biases in decision-making. There's also the interesting thing that correlation != causation, but people don't usually examine that too hard because it's difficult to examine all the variables, and much easier to reduce it down to 'this thing must be responsible for all these disparate ills' without looking at it hard enough.
For the record, I managed to get shafted in a variety of ways, one of them including eye problems, from what I thought was covid - I did not have the vaccine at the time. What it turned out to be was undiagnosed hypertension exacerbated by covid.
Well what do you think of a woman that works at the local hospital, she says the doctors usually saw 1 case of tongue cancer every 5 years (pretty rare), and after the vaccines they're seeing so many cases of tongue cancer that there is a waiting list for treatments. Is at least to be in doubt about it. What is inside those vaccines?
