Cipheron on 18/9/2023 at 11:17
Quote Posted by Azaran
A new study adds additional credibility to zinc as a Covid treatment
There are articles stating that people with a zinc deficiency have worse Covid outcomes.
This would neatly explain why some studies say zinc does nothing while others find it had a good effect. It depends on where you do the study if you're not actually controlling for zinc deficiency levels.
How i read the overall results is that people who NEED the zinc can benefit from it, but there's no actual evidence that just giving zinc to everyone will help.
(
https://www.sciencedirect.com/science/article/pii/S120197122030730X)
Quote:
Patients with coronavirus disease 2019 (COVID-19) had significantly low zinc levels in comparison to healthy controls.
Zinc deficient patients developed more complications (70.4% vs 30.0%, p = 0.009).
Zinc deficient COVID-19 patients had a prolonged hospital stay (7.9 vs 5.7 days, p = 0.048).
In vitro studies have shown that reduced zinc levels favour the interaction of angiotensin-converting enzyme 2 (ACE2) with severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) spike protein and likewise that increased zinc levels inhibit ACE2 expression resulting in reduced viral interaction.