Starker on 25/4/2020 at 16:08
"What do you have to lose":
Quote:
(
https://www.cnbc.com/2020/04/24/fda-issues-warnings-on-chloroquine-and-hydroxychloroquine-after-serious-poisoning-and-death-reported.html)
The Food and Drug Administration warned consumers Friday against taking malaria drugs chloroquine and hydroxychloroquine to treat Covid-19 outside a hospital or formal clinical trial setting after deaths and poisonings were reported.
The agency said patients taking the drugs for approved reasons, including malaria or to treat autoimmune conditions like lupus, should continue taking their medicine as prescribed.
The agency also said it became aware of reports of “serious heart rhythm problems” in patients with the virus who were treated with the malaria drugs, often in combination with antibiotic azithromycin, commonly known as a Z-Pak. It also warned physicians against prescribing the drugs to treat the coronavirus outside of a hospital.
“Hydroxychloroquine and chloroquine can cause abnormal heart rhythms such as QT interval prolongation and a dangerously rapid heart rate called ventricular tachycardia,” the agency wrote in the notice. “We will continue to investigate risks associated with the use of hydroxychloroquine and chloroquine for COVID-19 and communicate publicly when we have more information.”
The peer-reviewed Journal of the American Medical Association released a new study Friday that said researchers cut short a study testing chloroquine as a potential treatment for Covid-19 over safety concerns, citing a “primary outcome” of death. Nearly two dozen patients died and some developed irregular heart rates after taking doses of the drug daily.
[...]
lowenz on 25/4/2020 at 17:00
(
https://feinstein.northwell.edu/news/the-latest/largest-covid-19-study-of-hospitalized-patients-in-us-links-comorbidities-to-acuity)
+
(
https://jamanetwork.com/journals/jama/fullarticle/2765184?guestAccessKey=906e474e-0b94-4e0e-8eaa-606ddf0224f5&utm_source=For_The_Media&utm_medium=referral&utm_campaign=ftm_links&utm_content=tfl&utm_term=042220)
Maybe now you'll understand.
Ventilation doesn't make a difference 'cause it's a systemic disease.
ACEi and ARB medications can significantly increase mRNA expression of cardiac angiotensin-converting enzyme 2 (ACE2),11 leading to speculation about the possible adverse, protective, or biphasic effects of treatment with these medications.12 This is an important concern because these medications are the most prevalent antihypertensive medications among all drug classes.13 However, this case series design cannot address the complexity of this question, and the results are unadjusted for known confounders, including age, sex, race, ethnicity, socioeconomic status indicators, and comorbidities such as diabetes, chronic kidney disease, and heart failure.
Renzatic on 25/4/2020 at 17:00
If you all ever thought I was exaggerating the crap I see on my Facebook wall...
Inline Image:
https://i.imgur.com/lQGYwwt.jpg...and it just keeps going.
Gingerbread Man on 25/4/2020 at 17:26
Quote Posted by Starker
Branch Covidians
I love you.
SubJeff on 25/4/2020 at 23:05
Quote Posted by lowenz
Ventilation doesn't make a difference 'cause it's a systemic disease.
So no one should be ventilated?
lowenz on 25/4/2020 at 23:32
Quote Posted by SubJeff
So no one should be ventilated?
After you've solved (well, contained/reduced) the inflammation altering the blood vessel behaviour.
Otherwise there's no use, you keep pushing air in the lungs but there's simply no space for the O2/CO2 exchange (the interstitial pneumonia is due to multiple factors, ONE being the hyperemia+vessel expansion not only the endothelial direct damage related to the virus replication)
In NY there's a 90% of deaths among the ICU patients.....it's simply abysmal.
If you can avoid the inflammation (->Disseminated Intravascular Coagulation) the pneumonia (=the part of the pneumonia-like state not strictly related to the virus) maybe can be avoided too.
But the timings are really tighten up!
Yakoob on 26/4/2020 at 00:58
@Renz damn is that a public post shared in a group? The amount of comments make me feel that it isn't someone's personal post.
That's depressing. I also wonder how many of those are bots/fake accounts that just auto-respond to these things. Some of those replies just sound so generic/automatic.
Renzatic on 26/4/2020 at 01:02
It's a clip from a story one of my local news stations ran, probably grabbed right off of AP.
A lot of people seem to think that they're all Deep State propaganda fronts.
Pyrian on 26/4/2020 at 03:13
What really gets me about all the increases-in-disinfectant-exposure-cases stories is the baseline disinfectant exposure statistics.